Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.47 |
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568441 | 0.91 | MME (0.58) | MMEACEKMT2A | |
| SCHEMBL8451194 | 0.86 | MME (0.57) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL8452063 | 0.86 | MME (0.57) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL8447155 | 0.85 | MME (0.56) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL8450008 | 0.84 | MME (0.55) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL8446466 | 0.84 | MME (0.59) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL8451844 | 0.84 | MME (0.51) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL8446424 | 0.83 | MME (0.54) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL8452065 | 0.83 | MME (0.54) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL8450134 | 0.83 | MMEL1 (0.48) | MMEACETACR1CTSBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |