Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 5/20 | 0.45 |
| ▸ | ACE | P12821 | 5/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.38 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451250 | 0.94 | MME (0.45) | MMEL1MMEACECTSBNLRP3 | |
| SCHEMBL7567439 | 0.91 | MME (0.55) | MMEL1MMEACEPPARGPPARD | |
| SCHEMBL8450828 | 0.89 | MME (0.47) | MMEL1MMEACECTSBPOLB | |
| SCHEMBL8450271 | 0.89 | MME (0.49) | MMEL1MMEACECTSBNLRP3 | |
| SCHEMBL8449910 | 0.88 | MME (0.46) | MMEL1MMEACECTSBPOLB | |
| SCHEMBL8447126 | 0.88 | MME (0.46) | MMEL1MMEACECTSBPOLB | |
| SCHEMBL8447130 | 0.86 | MME (0.45) | MMEL1MMEACENLRP3RXRA | |
| SCHEMBL8449727 | 0.85 | MME (0.45) | MMEL1MMEACENLRP3RXRA | |
| SCHEMBL8452063 | 0.84 | MME (0.57) | MMEACECTSBPOLBTACR1 | |
| SCHEMBL8451194 | 0.84 | MME (0.57) | MMEACECTSBPOLBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |