Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.49 |
| ▸ | ACE | P12821 | 5/20 | 0.49 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451250 | 0.92 | MME (0.45) | MMEACEMMEL1RXRARXRB | |
| SCHEMBL8027621 | 0.90 | MME (0.65) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8523126 | 0.90 | MME (0.65) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8027626 | 0.90 | MME (0.65) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL7567439 | 0.89 | MME (0.55) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8450134 | 0.89 | MMEL1 (0.48) | MMEACEMMEL1RXRARXRB | |
| SCHEMBL8027609 | 0.87 | MME (0.66) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8451433 | 0.86 | MME (0.49) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL7569417 | 0.86 | MME (0.56) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL7569408 | 0.86 | MME (0.56) | MMEACEMMEL1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |