Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 12/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13048446 | 0.79 | EPHX1 (0.45) | LMNABLMEPHX1SMN1; SMN2RAB9A | |
| SCHEMBL10885385 | 0.79 | BLM (0.52) | LMNABLMEPHX1SMN1; SMN2RAB9A | |
| SCHEMBL28337863 | 0.79 | CPB2 (0.49) | LMNABLMEPHX1SMN1; SMN2RAB9A | |
| SCHEMBL11406503 | 0.79 | BLM (0.52) | LMNABLMEPHX1SMN1; SMN2RAB9A | |
| SCHEMBL10885389 | 0.79 | BLM (0.52) | LMNABLMEPHX1SMN1; SMN2RAB9A | |
| SCHEMBL24322687 | 0.79 | SMN1; SMN2 (0.55) | LMNABLMEPHX1SMN1; SMN2RAB9A | |
| SCHEMBL3592432 | 0.79 | CPB2 (0.49) | LMNABLMEPHX1SMN1; SMN2RAB9A | |
| SCHEMBL26896573 | 0.79 | EPHX1 (0.51) | LMNABLMEPHX1SMN1; SMN2RAB9A | |
| SCHEMBL22197609 | 0.78 | CPB2 (0.54) | LMNABLMEPHX1SMN1; SMN2RAB9A | |
| SCHEMBL22197608 | 0.78 | CPB2 (0.54) | LMNABLMEPHX1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591040-B1 | Quaternary basic amides as tachykinines antagonists | SANOFI SA (FR) | 1999-02-03 | — | — | EP | disclosed |
| EP-0591040-A1 | Quaternary basic amides as tachykinines antagonists | SANOFI (FR) | 1994-04-06 | — | — | EP | disclosed |