Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 5/20 | 0.73 |
| ▸ | MMP9 | P14780 | 13/20 | 0.69 |
| ▸ | MMP2 | P08253 | 12/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448511 | 0.91 | MMP9 (0.84) | KCNA5MMP9MMP2ADAM17 | |
| SCHEMBL8448503 | 0.90 | MMP9 (0.75) | KCNA5MMP9MMP2KCNH2ADAM17 | |
| SCHEMBL8448255 | 0.90 | MMP9 (0.82) | KCNA5MMP9MMP2KCNH2ADAM17 | |
| SCHEMBL8449351 | 0.90 | MMP9 (0.82) | KCNA5MMP9MMP2KCNH2ADAM17 | |
| SCHEMBL8451106 | 0.90 | MMP9 (0.67) | KCNA5MMP9MMP2KCNH2ADAM17 | |
| SCHEMBL8448286 | 0.89 | MMP9 (0.66) | KCNA5MMP9MMP2KCNH2ADAM17 | |
| SCHEMBL8448720 | 0.88 | MMP9 (0.65) | KCNA5MMP9MMP2KCNH2ADAM17 | |
| SCHEMBL8451063 | 0.87 | MMP9 (0.74) | KCNA5MMP9MMP2KCNH2ADAM17 | |
| SCHEMBL8450960 | 0.87 | MMP9 (0.71) | KCNA5MMP9MMP2KCNH2ADAM17 | |
| SCHEMBL8450882 | 0.85 | KCNA5 (0.62) | KCNA5MMP9MMP2KCNH2ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |