Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 12/20 | 0.82 |
| ▸ | MMP2 | P08253 | 11/20 | 0.82 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.62 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449351 | 1.00 | MMP9 (0.82) | MMP9MMP2KCNA5KCNH2NR3C1 | |
| SCHEMBL28340488 | 0.94 | KCNA5 (0.78) | MMP9MMP2KCNA5KCNH2NR3C1 | |
| SCHEMBL8448503 | 0.93 | MMP9 (0.75) | MMP9MMP2KCNA5KCNH2NR3C1 | |
| SCHEMBL8446521 | 0.90 | MMP9 (1.00) | MMP9MMP2KCNA5NR3C1ADAM17 | |
| SCHEMBL8446559 | 0.90 | MMP9 (1.00) | MMP9MMP2KCNA5NR3C1ADAM17 | |
| SCHEMBL8450863 | 0.90 | KCNA5 (0.73) | MMP9MMP2KCNA5KCNH2ADAM17 | |
| SCHEMBL8450960 | 0.89 | MMP9 (0.71) | MMP9MMP2KCNA5KCNH2ADAM17 | |
| SCHEMBL8448733 | 0.89 | MMP9 (0.82) | MMP9MMP2KCNA5NR3C1ADAM17 | |
| SCHEMBL8451106 | 0.88 | MMP9 (0.67) | MMP9MMP2KCNA5KCNH2ADAM17 | |
| SCHEMBL8451063 | 0.88 | MMP9 (0.74) | MMP9MMP2KCNA5KCNH2ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |