Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451004 | 1.00 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3PROKR1ACACB | |
| SCHEMBL8452651 | 0.91 | MAOB (0.39) | SLC6A2SLC6A4SLC6A3PROKR1ACACB | |
| SCHEMBL8452649 | 0.91 | MAOB (0.39) | SLC6A2SLC6A4SLC6A3PROKR1ACACB | |
| SCHEMBL8456006 | 0.90 | PROKR1 (0.35) | PROKR1FPR2DGAT1ESR2OPRL1 | |
| SCHEMBL8456014 | 0.90 | PROKR1 (0.35) | PROKR1FPR2DGAT1ESR2OPRL1 | |
| SCHEMBL8452526 | 0.90 | ESR2 (0.33) | CHRM4DGAT1MAOBESR2OPRL1 | |
| SCHEMBL8452531 | 0.90 | ESR2 (0.33) | CHRM4DGAT1MAOBESR2OPRL1 | |
| SCHEMBL8453692 | 0.89 | MAOA (0.35) | PROKR1FPR2MAOBFFAR4 | |
| SCHEMBL8453697 | 0.89 | MAOA (0.35) | PROKR1FPR2MAOBFFAR4 | |
| SCHEMBL8452274 | 0.89 | CNR1 (0.35) | DGAT1MAOBOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |