SCHEMBL8451642

SCHEMBL8451642

CCCC1COC(c2cccc(F)c2)OC1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.41
RCOR1 Q9UKL0 1/20 0.41
TAAR1 Q96RJ0 1/20 0.39
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38
CYP19A1 P11511 1/20 0.36
RIPK1 Q13546 1/20 0.36
TDP1 Q9NUW8 1/20 0.34
GRM2 Q14416 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
IDO1 P14902 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7861318 0.84 FYN (0.33)
SCHEMBL7861320 0.84 FYN (0.33)
SCHEMBL17783290 0.81 TAAR1 (0.41) KDM1ARCOR1TAAR1HTR2AHTR2C
SCHEMBL18560111 0.81 FASN (0.39) KDM1ARCOR1TAAR1HTR2AHTR2C
SCHEMBL8997307 0.81 KDM1A (0.36) KDM1ARCOR1HTR2AHTR2CHTR2B
SCHEMBL13381352 0.80 MEN1 (0.46) SMN1; SMN2
SCHEMBL8997270 0.80 HTR2A (0.36) KDM1ARCOR1HTR2AHTR2CHTR2B
SCHEMBL13381353 0.79 DRD2 (0.49) KDM1ARCOR1HTR2AHTR2CHTR2B
SCHEMBL17799313 0.78 KDM1A (0.45) KDM1ARCOR1
SCHEMBL7782316 0.78 KDM1A (0.32) KDM1ARCOR1HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5858272-A HAVING A LARGE .DELTA..EPSILON. WHILE MAINTAINING A HIGH VOLTAGE HOLDING RATIO; DRIVING THIN FILM TRANSISTOR AT LOW VOLTAGE; EXCELLANT COMPATIBILITY WITH CONVENTIONAL LIQUID CRYSALS; RELIABILITY CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0819685-A1 Phenyldioxane derivatives, liquid crystal compositions, and liquid crystal display elements Chisso Corporation (JP) 1998-01-21 EP disclosed