Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 13/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227814 | 0.89 | GRM5 (0.49) | ALDH1A1MAPTMEN1NPC1TP53 | |
| SCHEMBL229152 | 0.89 | GRM5 (0.49) | ALDH1A1MAPTMEN1NPC1TP53 | |
| SCHEMBL3961363 | 0.85 | RAB9A (0.44) | ALDH1A1MAPTMEN1NPC1TP53 | |
| SCHEMBL226477 | 0.82 | KMT2A (0.57) | ALDH1A1MAPTMEN1NPC1TP53 | |
| SCHEMBL230270 | 0.80 | GRM5 (0.44) | ALDH1A1MAPTMEN1NPC1TP53 | |
| SCHEMBL229747 | 0.76 | RAB9A (0.59) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL16741935 | 0.76 | CCR1 (0.52) | ALDH1A1MEN1NPC1TP53NFKB1 | |
| SCHEMBL230942 | 0.74 | GRM5 (0.47) | ALDH1A1MAPTMEN1NPC1TP53 | |
| SCHEMBL3957843 | 0.73 | GRM5 (0.58) | ALDH1A1MAPTMEN1NPC1TP53 | |
| SCHEMBL229174 | 0.73 | CXCR4 (0.45) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2436750-A2 | Ligand exchange thermochromic, (LETC), systems | Pleotint, L.L.C. (US) | 2012-04-04 | — | — | EP | disclosed |
| EP-2434000-A2 | Ligand exchange thermochromic, (LETC), systems | Pleotint, L.L.C. (US) | 2012-03-28 | — | — | EP | disclosed |
| EP-2082005-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | Pleotint, L.L.C. (US) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008028128-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, L.L.C. (US) | 2008-03-06 | — | — | WO | disclosed |