Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GRM5 | P41594 | 7/20 | 0.55 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.50 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226477 | 0.85 | KMT2A (0.57) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL229427 | 0.84 | RAB9A (0.72) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18162478 | 0.83 | MAPT (0.60) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3957843 | 0.83 | GRM5 (0.58) | RAB9AMEN1KMT2AALDH1A1GRM5 | |
| SCHEMBL1703679 | 0.82 | RAB9A (0.59) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30558522 | 0.82 | — | — | |
| SCHEMBL306134 | 0.82 | — | — | |
| SCHEMBL14599974 | 0.81 | ALDH1A1 (0.58) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL22454801 | 0.81 | GRM5 (0.49) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28965358 | 0.81 | ASIC3 (0.50) | RAB9AMEN1KMT2AALDH1A1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8182718-B2 | Ligand exchange thermochromic systems and high ε ligands for same | PLEOTINT, L.L.C. (US) | 2012-05-22 | — | — | US | claimed |
| US-9465239-B2 | Color neutral thermochromic layers and laminates | PLEOTINT, L.L.C. (US) | 2016-10-11 | — | — | US | disclosed |
| US-9011734-B2 | Ligand exchange thermochromic, (LETC), systems | PLEOTINT, L.L.C. (US) | 2015-04-21 | — | — | US | disclosed |
| US-20140327952-A1 | COLOR NEUTRAL THERMOCHROMIC LAYERS AND LAMINATES | PLEOTINT, L.L.C. (US) | 2014-11-06 | — | — | US | disclosed |
| EP-2082005-B9 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT LLC (US) | 2013-05-22 | — | — | EP | disclosed |
| US-8431045-B2 | Ligand exchange thermochromic systems and high ε ligands for same | PLEOTINT, L.L.C. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120292581-A1 | LIGAND EXCHANGE THERMOCHROMIC SYSTEMS AND HIGH E LIGANDS FOR SAME | PLEOTINT, LLC (US) | 2012-11-22 | — | — | US | disclosed |
| EP-2082005-B1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| US-8182718-B2 | Ligand exchange thermochromic systems and high ε ligands for same | PLEOTINT, L.L.C. (US) | 2012-05-22 | — | — | US | disclosed |
| EP-2436750-A2 | Ligand exchange thermochromic, (LETC), systems | Pleotint, L.L.C. (US) | 2012-04-04 | — | — | EP | disclosed |
| US-7542196-B2 | Ligand exchange thermochromic, (LETC), systems | PLEOTINT, L.L.C. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7538931-B2 | Ligand exchange thermochromic systems containing exchange metals | PLEOTINT, L.L.C. (US) | 2009-05-26 | — | — | US | disclosed |
| US-7525717-B2 | reversible; laminated; transition metal ion coordinated with a high epsilon ligand and a low epsilon ligand; polymer; separator; variable light transmission windows; polyvinyl butyral; nickel or cobalt iodide ligands; diol, triol or polyol ligands | PLEOTINT, L.L.C. (US) | 2009-04-28 | — | — | US | disclosed |
| US-20080105851-A1 | Exhibiting a reversible change in absorbance of electromagnetic radiation as the temperature of the system is reversibly changed; comprising a transition metal ion and a ligand | PLEOTINT, LLC (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080106781-A1 | LIGAND EXCHANGE THERMOCHROMIC SYSTEMS CONTAINING EXCHANGE METALS | PLEOTINT, LLC (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080100903-A1 | MULTI-LAYER LIGAND EXCHANGE THERMOCHROMIC SYSTEMS | PLEOTINT, LLC (US) | 2008-05-01 | — | — | US | disclosed |
| US-20080100902-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, LLC (US) | 2008-05-01 | — | — | US | disclosed |
| WO-2008028128-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, L.L.C. (US) | 2008-03-06 | — | — | WO | disclosed |
| US-20060058178-A1 | Aromatic compounds containing nitrogen and p- functionalized amines, the production thereof and their use in catalytic reactions | DEGUSSA AG (DE) | 2006-03-16 | — | — | US | disclosed |
| EP-1446224-B1 | AROMATIC COMPOUNDS CONTAINING NITROGEN AND P-FUNCTIONALIZED AMINES, THE PRODUCTION THEREOF AND THEIR USE IN CATALYTIC REACTIONS | DEGUSSA (DE) | 2006-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058178-A1 | Aromatic compounds containing nitrogen and p- functionalized amines, the production thereof and their use in catalytic reactions | PAH, PNMT, TYR | RAB9A 2334/4885MEN1 3253/4885KMT2A 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.