SCHEMBL845296

SCHEMBL845296

O=C1NC(=O)C(Br)=C1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18835139 0.82 CA1 (0.33)
SCHEMBL1164153 0.79
SCHEMBL1163962 0.72 GSK3B (0.58)
SCHEMBL6851025 0.71 GSK3B (0.44)
SCHEMBL3470127 0.71
SCHEMBL11886044 0.71 PTGS2 (0.31)
SCHEMBL3469703 0.71
SCHEMBL31028444 0.69
SCHEMBL29470022 0.67 CA1 (0.46)
SCHEMBL465112 0.67 CA1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 958 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735958-A1 PHOTORESIST PATTERNING IN MULTI-DEPTH NANOWELLS Illumina, Inc. (US) 2026-05-06 EP claimed
EP-4727596-A2 ANTIBODY-DRUG CONJUGATES AND LINKERS AND METHODS OF USE THEREOF Ohio State Innovation Foundation (US) 2026-04-22 EP claimed
EP-4727977-A2 CD276 ANTIBODY AND METHODS OF USE THEREOF Ohio State Innovation Foundation (US) 2026-04-22 EP claimed
US-12479792-B2 Compositions of chelating molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-11-25 US claimed
US-20250312472-A1 ANTIBODY COMPOUNDS WITH REACTIVE CYSTEINE AND RELATED ANTIBODY DRUG CONJUGATES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2025-10-09 US claimed
EP-4565281-A1 SITE-SPECIFIC MODIFICATION BY A BBB-SHUTTLE OF ANTIBODY-BASED ENTITIES FOR CROSSING THE BLOOD-BRAIN BARRIER Gate2Brain, S.L. (ES) 2025-06-11 EP claimed
CN-119947759-A Site-specific modification of BBB-shuttling agents through antibody-based entities for crossing the blood brain barrier 盖特2布莱恩有限责任公司 2025-05-06 CN claimed
WO-2025090525-A1 LIPID NANOPARTICLES FOR DELIVERY OF THERAPEUTIC PAYLOADS TO T CELLS TESSERA THERAPEUTICS, INC. (US) 2025-05-01 WO claimed
CN-119524153-A DAR1 antibody drug conjugate and preparation method and application thereof 上海药明合联生物技术有限公司 2025-02-28 CN claimed
WO-2025019334-A2 ANTIBODY-DRUG CONJUGATES AND LINKERS AND METHODS OF USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2025-01-23 WO claimed
US-6812243-B2 AS TYROSINE KINASE INHIBITORS; FOR THERARPY OF TUMORS, ARTERIOSCLEROSIS, RESTENOSIS AFTER BALLOON ANGIOPLASTY, ARTHRITIS AND FIBROTIC DISEASES ZENTARIS AG (DE) 2004-11-02 US claimed
WO-2004083202-A1 A PROCESS FOR THE PREPARATION OF INDOLYMALEIMIDES SUVEN LIFE SCIENCES LIMITED (IN) 2004-09-30 WO claimed
US-20030008898-A1 Indole derivatives and their use for the treatment of malignant and other diseases based on pathological proliferation ZENTARIS AG (DE) 2003-01-09 US claimed
EP-1109785-B1 INDOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF MALIGNANT AND OTHER DISEASES CAUSED BY PATHOLOGICAL CELL PROLIFERATION ZENTARIS AG (DE) 2003-01-02 EP claimed
EP-0397060-B1 Maleinimide derivatives and their use as medicines GOEDECKE AG (DE) 2001-11-21 EP claimed
CN-1310705-A Indole derivatives and their use in the treatment of malignant and other diseases caused by pathological cell proliferation ASTA MEDICA AG (DE) 2001-08-29 CN claimed
EP-0370236-B1 INDOLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS GÖDECKE AKTIENGESELLSCHAFT (DE) 1991-12-27 EP claimed
US-4925897-A DIELS-ALDER REATION WITH A HALOGENATED MALEIC ANHYDRIDE OR MALEIMIDE, AN AMINOQUINONE OR TRIAZOLINE BASF AKTIENGESELLSCHAFT (DE) 1990-05-15 US claimed
US-4680272-A Method for detecting molecules containing amine or thiol groups UNIVERSITY OF CALIFORNIA (US) 1987-07-14 US claimed
US-4030926-A Light-sensitive material containing a dye-forming combination of a heterocyclic compound and a cyclic dihalodicarbonyl compound in a polymeric binder AGFA-GEVAERT, A.G. (DT) 1977-06-21 US claimed