Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447366 | 0.90 | MME (0.47) | ALDH1A1KMT2AMAPTLMNAGAA | |
| SCHEMBL8454133 | 0.89 | CYP26A1 (0.51) | ALDH1A1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL8447834 | 0.88 | CYP26A1 (0.45) | ALDH1A1MAPTLMNAKDM4EFFAR1 | |
| SCHEMBL8451866 | 0.87 | MME (0.50) | KMT2AFFAR1MMEACECYP26A1 | |
| SCHEMBL8452086 | 0.87 | MME (0.46) | ALDH1A1KMT2AKDM4EMMEACE | |
| SCHEMBL8452846 | 0.85 | POLB (0.43) | ALDH1A1KMT2AFFAR1MMEACE | |
| SCHEMBL8447801 | 0.80 | MME (0.52) | MMEACESLC6A4 | |
| SCHEMBL8032858 | 0.80 | MME (0.61) | KMT2AMMEACE | |
| SCHEMBL8032865 | 0.80 | MME (0.61) | KMT2AMMEACE | |
| SCHEMBL8127278 | 0.79 | MAPT (0.50) | ALDH1A1KMT2AMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |