Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.47 |
| ▸ | ACE | P12821 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453232 | 0.90 | ALDH1A1 (0.43) | MMEACEKMT2AALDH1A1GAA | |
| SCHEMBL8451302 | 0.88 | KMT2A (0.53) | MMEACEKMT2AALDH1A1HTT | |
| SCHEMBL8453630 | 0.85 | MME (0.51) | MMEACEALDH1A1LMNACYP26A1 | |
| SCHEMBL8448437 | 0.85 | MME (0.63) | MMEACEKMT2ASMN1; SMN2CYP26A1 | |
| SCHEMBL8447368 | 0.85 | MME (0.58) | MMEACEKMT2AALDH1A1LMNA | |
| SCHEMBL8451301 | 0.84 | MME (0.50) | MMEACESMN1; SMN2CYP26A1 | |
| SCHEMBL8455915 | 0.83 | MME (0.48) | MMEACEKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8030339 | 0.80 | MME (0.74) | MMEACEKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8030346 | 0.80 | MME (0.74) | MMEACEKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8448568 | 0.79 | MME (0.63) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |