Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.47 |
| ▸ | ACE | P12821 | 6/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8456179 | 0.93 | MME (0.47) | MMEACEAOC3ALDH1A1LMNA | |
| SCHEMBL8447368 | 0.90 | MME (0.58) | MMEACEITGB3ITGA2BITGAV | |
| SCHEMBL8455768 | 0.88 | MME (0.53) | MMEACEAOC3POLB | |
| SCHEMBL8448596 | 0.87 | MME (0.47) | MMEACESMN1; SMN2CYP26A1ALDH1A1 | |
| SCHEMBL8452086 | 0.86 | MME (0.46) | MMEACESMN1; SMN2CYP26A1ALDH1A1 | |
| SCHEMBL8447608 | 0.84 | MME (0.47) | MMEACESMN1; SMN2 | |
| SCHEMBL8452949 | 0.84 | MME (0.54) | MMEACEITGB3ITGA2BITGAV | |
| SCHEMBL8447380 | 0.84 | POLB (0.47) | MMEACESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8452366 | 0.83 | MME (0.46) | MMEACEITGB3ITGA2BITGAV | |
| SCHEMBL8448437 | 0.81 | MME (0.63) | MMEACESMN1; SMN2CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |