Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453574 | 1.00 | SPHK1 (0.34) | SPHK1DGAT1CYP2C9GPR84PRCP | |
| SCHEMBL8452698 | 0.93 | MAOA (0.38) | SPHK1DGAT1CYP2C9GPR84PRCP | |
| SCHEMBL8452690 | 0.93 | MAOA (0.38) | SPHK1DGAT1CYP2C9GPR84PRCP | |
| SCHEMBL8451031 | 0.93 | GPR84 (0.38) | GPR84PRCPCYP11B1CYP11B2RARA | |
| SCHEMBL8451029 | 0.93 | GPR84 (0.38) | GPR84PRCPCYP11B1CYP11B2RARA | |
| SCHEMBL8453455 | 0.91 | SPHK1 (0.43) | SPHK1CYP2C9RARARARBRARG | |
| SCHEMBL8453459 | 0.91 | SPHK1 (0.43) | SPHK1CYP2C9RARARARBRARG | |
| SCHEMBL8451822 | 0.91 | MAOB (0.38) | SPHK1DGAT1GPR84PRCPESR2 | |
| SCHEMBL8451826 | 0.91 | MAOB (0.38) | SPHK1DGAT1GPR84PRCPESR2 | |
| SCHEMBL8451079 | 0.91 | SPHK1 (0.36) | SPHK1CYP2C9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |