Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 17/20 | 0.65 |
| ▸ | KDR | P35968 | 17/20 | 0.65 |
| ▸ | FGFR1 | P11362 | 14/20 | 0.65 |
| ▸ | FLT4 | P35916 | 12/20 | 0.65 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 11/20 | 0.64 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.62 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2203010 | 0.91 | FLT1 (0.73) | FLT1KDRFGFR1FLT4EPHB2 | |
| Hydrochloric Acid SCHEMBL7477739 | 0.90 | FLT1 (0.75) | FLT1KDRFGFR1FLT4EPHB2 | |
| SCHEMBL5783910 | 0.84 | FLT1 (0.80) | FLT1KDRFGFR1FLT4EPHB2 | |
| SCHEMBL5428437 | 0.84 | FLT1 (0.80) | FLT1KDRFGFR1FLT4EPHB2 | |
| SCHEMBL2200924 | 0.82 | KDR (0.74) | FLT1KDRFGFR1FLT4EPHB2 | |
| SCHEMBL1008026 | 0.82 | KDR (0.72) | FLT1KDRFGFR1FLT4EPHB2 | |
| Hydrochloric Acid SCHEMBL6454560 | 0.81 | KDR (0.71) | FLT1KDRFGFR1FLT4EPHB2 | |
| Water SCHEMBL27735443 | 0.81 | KDR (0.71) | FLT1KDRFGFR1FLT4EPHB2 | |
| SCHEMBL3012896 | 0.81 | KDR (1.00) | FLT1KDRFGFR1FLT4EPHB2 | |
| SCHEMBL29365791 | 0.81 | KDR (1.00) | FLT1KDRFGFR1FLT4EPHB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929530-A1 | QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZENECA LIMITED (GB) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013354-A1 | QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZENECA LIMITED (GB) | 1998-04-02 | — | — | WO | disclosed |