SCHEMBL845454

SCHEMBL845454

CCCCCCN(NC(=O)O)C(=O)OCC

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 7/20 0.40
KDM4C Q9H3R0 7/20 0.40
PHF8 Q9UPP1 4/20 0.40
ZDHHC7 Q9NXF8 1/20 0.39
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KDM5C P41229 1/20 0.37
KDM5B Q9UGL1 1/20 0.37
EPHX1 P07099 1/20 0.37
DNM1 Q05193 1/20 0.37
KDM4A O75164 2/20 0.36
PAM P19021 2/20 0.36
NPC1 O15118 1/20 0.36
JAK2 O60674 1/20 0.36
RAB9A P51151 1/20 0.36
PAX8 Q06710 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11783270 0.85 MGAM (0.41) MEN1MAPTKMT2AL3MBTL1
SCHEMBL4555636 0.85 ALOX15 (0.36) KDM5AKDM4CPHF8ZDHHC7MEN1
SCHEMBL8648404 0.82 GPR84 (0.40) KDM5AKDM4CPHF8MEN1KMT2A
SCHEMBL11784898 0.77 HCAR2 (0.37)
SCHEMBL25271947 0.76 CA12 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL25227673 0.76 CA12 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL6897040 0.76 CA12 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL25275015 0.76 CA12 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL4647473 0.76 CA12 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL25276950 0.76 CA12 (0.45) MEN1MAPTKMT2AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120095152-A1 ADHESION-PROMOTING SYSTEM FOR RUBBER GOODS CYTEC SURFACE SPECIALTIES GERMANY GMBH (DE) 2012-04-19 US disclosed
EP-2432810-A1 ADHESION-PROMOTING SYSTEM FOR RUBBER GOODS Cytec Surface Specialties Germany GmbH (DE) 2012-03-28 EP disclosed