Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.70 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776358 | 1.00 | NAAA (0.70) | NAAAKEAP1NFE2L2EPHX1NAMPT | |
| SCHEMBL9036296 | 0.93 | NAAA (0.64) | NAAAKEAP1NFE2L2EPHX1NAMPT | |
| SCHEMBL9035898 | 0.93 | NAAA (0.64) | NAAAKEAP1NFE2L2EPHX1NAMPT | |
| SCHEMBL2115641 | 0.91 | NAAA (0.61) | NAAAKEAP1NFE2L2EPHX1NAMPT | |
| SCHEMBL17172545 | 0.91 | NAAA (0.82) | NAAAKEAP1NFE2L2EPHX1NAMPT | |
| SCHEMBL9034167 | 0.87 | NAAA (0.56) | NAAAKEAP1NFE2L2EPHX1NAMPT | |
| SCHEMBL9034554 | 0.85 | NAAA (0.58) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 | |
| SCHEMBL1740262 | 0.85 | NAAA (0.58) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 | |
| SCHEMBL9035265 | 0.83 | NAAA (0.55) | NAAAKEAP1NFE2L2EPHX1NAMPT | |
| SCHEMBL1689436 | 0.83 | KMT2A (0.50) | NAAAKEAP1NFE2L2EPHX1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691327-B1 | AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME | KAO CORP (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5723497-A | AMINE ALCOHOL DERIVATIVES FOR WRINKLE RESISTNCE | KAO CORPORATION (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0691327-A1 | AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME | Kao Corporation (JP) | 1996-01-10 | — | — | EP | disclosed |