Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115641 | 0.96 | NAAA (0.61) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 | |
| SCHEMBL9035898 | 0.94 | NAAA (0.64) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 | |
| SCHEMBL9036296 | 0.94 | NAAA (0.64) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 | |
| SCHEMBL1689436 | 0.92 | KMT2A (0.50) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 | |
| SCHEMBL28066295 | 0.88 | NAAA (0.50) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 | |
| SCHEMBL8455292 | 0.87 | NAAA (0.70) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 | |
| SCHEMBL9776358 | 0.87 | NAAA (0.70) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 | |
| SCHEMBL9035265 | 0.83 | NAAA (0.55) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 | |
| SCHEMBL1740262 | 0.82 | NAAA (0.58) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 | |
| SCHEMBL9034554 | 0.82 | NAAA (0.58) | NAAAKEAP1NFE2L2EPHX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |