Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.39 |
| ▸ | EEF2K | O00418 | 2/20 | 0.37 |
| ▸ | EEF2 | P13639 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337902 | 0.82 | TRIM24 (0.50) | TLR8EEF2KEEF2MEN1PLK4 | |
| SCHEMBL9750772 | 0.81 | TRIM24 (0.48) | EEF2KEEF2MEN1PLK4JAK2 | |
| SCHEMBL28101657 | 0.80 | CA1 (0.38) | CA1CA2TLR8EEF2KEEF2 | |
| SCHEMBL19964543 | 0.79 | — | — | |
| SCHEMBL1607919 | 0.76 | TRIM24 (0.52) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL31287324 | 0.76 | ALDH1A1 (0.33) | CA1CA2NPC1RAB9AALDH1A1 | |
| SCHEMBL29226988 | 0.76 | NPC1 (0.35) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9664699 | 0.73 | EEF2K (0.44) | CA1CA2TLR8EEF2KEEF2 | |
| SCHEMBL18433170 | 0.72 | EEF2K (0.46) | CA1CA2TLR8EEF2KEEF2 | |
| SCHEMBL2973033 | 0.72 | TLR8 (0.46) | TLR8EEF2KEEF2MEN1PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623619-B1 | PREPARATION METHOD OF ARENO[e]INDOLS | PHARMA MAR S A PHARMAR (ES) | 1999-02-03 | — | — | EP | claimed |
| EP-0623619-B1 | PREPARATION METHOD OF ARENO[e]INDOLS | PHARMA MAR S A PHARMAR (ES) | 1999-02-03 | — | — | EP | disclosed |