Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | EEF2K | O00418 | 2/20 | 0.39 |
| ▸ | EEF2 | P13639 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | GALR3 | O60755 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337902 | 0.98 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1NPC1RAB9A | |
| SCHEMBL1607919 | 0.93 | TRIM24 (0.52) | TRIM24TRIM33ALDH1A1NPC1RAB9A | |
| SCHEMBL9225514 | 0.85 | TRIM24 (0.55) | TRIM24TRIM33ALDH1A1NPC1RAB9A | |
| SCHEMBL27246698 | 0.83 | TRIM24 (0.44) | TRIM24TRIM33ALDH1A1NPC1RAB9A | |
| SCHEMBL8455609 | 0.81 | CA1 (0.44) | ALDH1A1NPC1RAB9AEEF2KEEF2 | |
| SCHEMBL6015786 | 0.81 | TRIM24 (0.46) | TRIM24TRIM33ALDH1A1NPC1RAB9A | |
| SCHEMBL11878285 | 0.79 | FABP4 (0.43) | TRIM24TRIM33ALDH1A1MAPTPTGS1 | |
| SCHEMBL11871741 | 0.79 | FABP4 (0.43) | TRIM24TRIM33ALDH1A1MAPTPTGS1 | |
| SCHEMBL28101657 | 0.79 | CA1 (0.38) | ALDH1A1NPC1RAB9AEEF2KEEF2 | |
| SCHEMBL10852053 | 0.79 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004560-A | Polycondensation In The Presence Of A Condensing Agent, i.e. Acid Chloride, Acid Anhydride, Strong Acid Or Hygroscopic Compound; Electroconducting, Semiconducting Properties | WACKER-CHEMIE GMBH (DE) | 1991-04-02 | — | — | US | disclosed |
| EP-0285021-A2 | Basic polypyrrylenmethines and their salts | WACKER-CHEMIE GMBH (DE) | 1988-10-05 | — | — | EP | disclosed |