SCHEMBL8455960

SCHEMBL8455960

C1=CC(OC(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 1/20 0.32
KIF11 P52732 1/20 0.32
SIGMAR1 Q99720 2/20 0.31
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
RET P07949 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30718139 0.78 RET (0.35) HTR6HTR2ASIGMAR1RET
SCHEMBL5033507 0.78 RET (0.35) HTR6HTR2ASIGMAR1RET
SCHEMBL29723819 0.72 SLC6A2 (0.38) HTR6HTR2ASIGMAR1RET
SCHEMBL7197990 0.71 HTR2A (0.38) HTR6HTR2ASIGMAR1RET
SCHEMBL1680359 0.71 RET (0.38) HTR6HTR2ASIGMAR1RET
SCHEMBL5150447 0.71 HTR2A (0.38) HTR6HTR2ASIGMAR1RET
SCHEMBL1680358 0.71 HTR2A (0.38) HTR6HTR2ASIGMAR1RET
SCHEMBL28285223 0.71 HTR2A (0.42) HTR6HTR2ASIGMAR1ALDH1A1ALOX15
SCHEMBL27714402 0.70 HTR2A (0.34) HTR6HTR2ASIGMAR1ALDH1A1RET
SCHEMBL30931450 0.69 POLB (0.38) HTR6HTR2ASIGMAR1ALDH1A1RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553107-B1 PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY PROCYON PHARM INC (US) 1999-09-29 EP claimed