Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290935 | 0.79 | RET (0.36) | RET | |
| SCHEMBL15499549 | 0.79 | CA4 (0.35) | KDM4EADRA2BADRA2CHTR2CMEN1 | |
| SCHEMBL5150447 | 0.78 | HTR2A (0.38) | RETHTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL1680358 | 0.78 | HTR2A (0.38) | RETHTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL7197990 | 0.78 | HTR2A (0.38) | RETHTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL5033507 | 0.78 | RET (0.35) | RETHTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL4516491 | 0.78 | RET (0.42) | RETHTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL9495808 | 0.78 | RET (0.35) | RETHTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL5718857 | 0.78 | RET (0.35) | RETHTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL30718139 | 0.78 | RET (0.35) | RETHTR2AHTR6KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600807-B2 | Polypropylene film with improved slip performance | BOREALIS AG (AT) | 2026-04-14 | — | — | US | disclosed |
| US-12571144-B2 | Light weight melt blown webs with improved barrier properties | BOREALIS AG (AT) | 2026-03-10 | — | — | US | disclosed |
| US-12545780-B2 | Flexible metal clad laminates and methods of preparation thereof | NOTARK CORPORATION (US) | 2026-02-10 | — | — | US | disclosed |
| US-12539477-B2 | Filtration media made from melt-blown fibers with improved filtration properties | BOREALIS AG (AT) | 2026-02-03 | — | — | US | disclosed |
| US-12447719-B2 | Metal-clad laminate, wiring board, resin-including metal foil, and resin composition | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2025-10-21 | — | — | US | disclosed |
| EP-4034579-B1 | CATALYSTS | BOREALIS AG (AT) | 2025-07-23 | — | — | EP | disclosed |
| US-12319772-B2 | Catalysts | BOREALIS AG (AT) | 2025-06-03 | — | — | US | disclosed |
| US-12312452-B2 | Resin composition, prepreg, film with resin, metal foil with resin, metal-clad laminate, and wiring board | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2025-05-27 | — | — | US | disclosed |
| US-12233621-B2 | Copper-clad laminated plate, resin-clad copper foil, and circuit substrate using said plate and foil | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2025-02-25 | — | — | US | disclosed |
| WO-2024219272-A1 | CURABLE RESIN COMPOSITION AND CURED PRODUCT OF SAME | 日本化薬株式会社 | 2024-10-24 | — | — | WO | disclosed |
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6127579-A | REACTING AN INDANYL ETHER UNDER BASIC CONDITIONS TO GIVE A NOVEL SUBSTANCE WHICH IS THE INDENYL ETHER DERIVATIVE AND HYDROLYZING THIS TO GIVE THE 1-INDANONE | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 2000-10-03 | — | — | US | disclosed |
| EP-0968991-A1 | Method of manufacturing 1-indanone | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 2000-01-05 | — | — | EP | disclosed |
| EP-0548235-A4 | SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES | UNIV CALIFORNIA (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0699069-A4 | — | — | 1996-04-03 | — | — | EP | disclosed |
| EP-0699069-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994025013-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-11-10 | — | — | WO | disclosed |
| EP-0548235-A1 | SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005178-A1 | SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | DPP4, DPP9, DPP7 | RET 857/4885HTR2A 1359/4885HTR6 548/4885 |
| US-12319772-B2 | Catalysts | SIGMAR1, C1S, CYCS | RET 954/4885HTR2A 1426/4885HTR6 1870/4885 |
| US-12600807-B2 | Polypropylene film with improved slip performance | CCRL2, CCR1, CCR6 | RET 2332/4885HTR2A 1389/4885HTR6 653/4885 |
| US-12571144-B2 | Light weight melt blown webs with improved barrier properties | HMGB2, HMOX2, HPGDS | RET 3759/4885HTR2A 258/4885HTR6 512/4885 |
| US-12539477-B2 | Filtration media made from melt-blown fibers with improved filtration properties | MACF1, MIF, TGFBR2 | RET 3117/4885HTR2A 540/4885HTR6 1078/4885 |
| US-12545780-B2 | Flexible metal clad laminates and methods of preparation thereof | DSG1, CDH1, CAD | RET 4581/4885HTR2A 112/4885HTR6 2205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.