Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CCL2 | P13500 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5150447 | 0.78 | HTR2A (0.38) | HTR2AHTR6RETSIGMAR1CYP2D6 | |
| SCHEMBL1680359 | 0.78 | RET (0.38) | HTR2AHTR6RETSIGMAR1CYP2D6 | |
| SCHEMBL7197990 | 0.78 | HTR2A (0.38) | HTR2AHTR6RETSIGMAR1CYP2D6 | |
| SCHEMBL5718862 | 0.78 | RET (0.39) | HTR2AHTR6RETSIGMAR1CYP2D6 | |
| SCHEMBL29723819 | 0.75 | SLC6A2 (0.38) | HTR2AHTR6RETSIGMAR1SLC6A2 | |
| SCHEMBL5370598 | 0.74 | HTR2A (0.34) | HTR2AHTR6RETCYP2D6KDM4E | |
| SCHEMBL6700611 | 0.74 | POLB (0.39) | HTR2AHTR6RETSIGMAR1CYP2D6 | |
| SCHEMBL5033507 | 0.74 | RET (0.35) | HTR2AHTR6RETSIGMAR1CYP2D6 | |
| SCHEMBL9495808 | 0.74 | RET (0.35) | HTR2AHTR6RETSIGMAR1CYP2D6 | |
| SCHEMBL4516491 | 0.74 | RET (0.42) | HTR2AHTR6RETSIGMAR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142611-B2 | Aliphatic polycarbonate resin for forming partition, partition material, substrate and production method therefor, production method for wiring substrate, and wiring forming method | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2021-10-12 | — | — | US | disclosed |
| US-20190119440-A1 | ALIPHATIC POLYCARBONATE RESIN FOR FORMING PARTITION, PARTITION MATERIAL, SUBSTRATE AND PRODUCTION METHOD THEREFOR, PRODUCTION METHOD FOR WIRING SUBSTRATE, AND WIRING FORMING METHOD | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2019-04-25 | — | — | US | disclosed |
| EP-3441417-A1 | ALIPHATIC POLYCARBONATE RESIN FOR FORMING PARTITION, PARTITION MATERIAL, SUBSTRATE AND PRODUCTION METHOD THEREFOR, PRODUCTION METHOD FOR WIRING SUBSTRATE, AND WIRING FORMING METHOD | Sumitomo Seika Chemicals CO. LTD. (JP) | 2019-02-13 | — | — | EP | disclosed |
| US-20110195999-A1 | NOVEL ANTIFUNGAL AGENT CONTAINING HETEROCYCLIC COMPOUND | NAKAMOTO KAZUTAKA | 2011-08-11 | — | — | US | disclosed |
| US-7932272-B2 | Antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-04-26 | — | — | US | disclosed |
| US-7829585-B2 | Antifungal agent containing pyridine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20090062348-A1 | Antifungal Agent Containing Pyridine Derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1864980-A1 | ANTIFUNGAL AGENT CONTAINING PYRIDINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2007-12-12 | — | — | EP | disclosed |
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| US-7074798-B2 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1669348-A1 | NOVEL ANTIFUNGAL AGENT COMPRISING HETEROCYCLIC COMPOUND | Eisai Co., Ltd. (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | DPP4, DPP9, DPP7 | HTR2A 1359/4885HTR6 548/4885RET 857/4885 |
| US-20110195999-A1 | NOVEL ANTIFUNGAL AGENT CONTAINING HETEROCYCLIC COMPOUND | ERG28, CYP51A1, XPO1 | HTR2A 3780/4885HTR6 4269/4885RET 4438/4885 |
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | ERG28, DPM1, CYP51A1 | HTR2A 3773/4885HTR6 4266/4885RET 4478/4885 |
| US-20090062348-A1 | Antifungal Agent Containing Pyridine Derivative | ERG28, SQOR, CYP51A1 | HTR2A 3565/4885HTR6 3055/4885RET 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.