SCHEMBL8456124

SCHEMBL8456124

FCCC=C[C@H]1CC[C@H](c2ccc(Cl)c(F)c2)CC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
HTR7 P34969 1/20 0.31
PANK3 Q9H999 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8456120 1.00 SLC6A3 (0.32) SLC6A3SLC6A2SLC6A4HTR7PANK3
SCHEMBL8454248 0.96 SLC6A2 (0.30) SLC6A3SLC6A2SLC6A4
SCHEMBL8454242 0.96 SLC6A2 (0.30) SLC6A3SLC6A2SLC6A4
SCHEMBL8453712 0.94 OPRL1 (0.33)
SCHEMBL8453717 0.94 OPRL1 (0.33)
SCHEMBL8452105 0.90 DGAT1 (0.31)
SCHEMBL8452116 0.90 DGAT1 (0.31)
SCHEMBL8452107 0.90 DGAT1 (0.31)
SCHEMBL8452114 0.90 DGAT1 (0.31)
SCHEMBL8448975 0.87 HTR2A (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679707-B1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 1999-06-16 EP disclosed
US-5720899-A Liquid crystalline compound, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1998-02-24 US disclosed
US-5653911-A Liquid crystalline compound liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1997-08-05 US disclosed
EP-0679707-A1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1995-11-02 EP disclosed