Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8456484 | 1.00 | KDM4E (0.46) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL11974557 | 0.89 | SOAT1 (0.46) | KDM4ESOAT1PLA2G4AFAAHPPARG | |
| SCHEMBL11247462 | 0.86 | KDM4E (0.50) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL11604196 | 0.86 | KDM4E (0.50) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL14642098 | 0.83 | SOAT1 (0.44) | KDM4ESOAT1PLA2G4AFAAHPPARG | |
| SCHEMBL11805433 | 0.83 | ALDH1A1 (0.43) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL11805446 | 0.83 | ALDH1A1 (0.43) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL14938454 | 0.81 | — | — | |
| SCHEMBL7072455 | 0.81 | — | — | |
| SCHEMBL7072454 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | claimed |
| US-5961483-A | Iontophoretic delivery of cell adhesion inhibitors | COLLATERAL AGENTS, LLC | 1999-10-05 | — | — | US | disclosed |
| US-5935598-A | DEVICE FOR NON-INVASIVE ADMINISTRATION OF A CELL ADHESION RECEPTOR ANTAGONIST TO A MAMMAL; CURRENT DISTRIBUTING MEMBER, IONIZABLE ANTAGONIST RESERVOIR, ELECTROLYTE RESERVOIR, POWDER SOURCE; TREATING THROMBOSIS, ANTICOAGULANTS | BECTON DICKINSON RESEARCH CENTER (US) | 1999-08-10 | — | — | US | disclosed |
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |