Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | KDM5C | P41229 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247462 | 1.00 | KDM4E (0.50) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL10300840 | 0.87 | SOAT1 (0.51) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL8456478 | 0.86 | KDM4E (0.46) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL8456484 | 0.86 | KDM4E (0.46) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL1431692 | 0.82 | SOAT1 (0.47) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL1431691 | 0.82 | SOAT1 (0.47) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL28428639 | 0.82 | ALDH1A1 (0.50) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL28708860 | 0.82 | KDM4E (0.46) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL7998543 | 0.82 | MAPT (0.36) | SOAT1ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL11819753 | 0.81 | ALDH1A1 (0.48) | KDM4EKDM6BKDM5CEGLN1PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160215012-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (IL) | 2016-07-28 | — | — | US | disclosed |
| US-4073799-A | Process for producing 3-formylcyclopentanone derivatives | (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JA) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215012-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | C9, AMPD3, C5 | KDM4E 3936/4885KDM6B 2107/4885KDM5C 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.