Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2618716 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAPTDGKALMNACYP3A4 | |
| SCHEMBL3906803 | 0.84 | CYP1A2 (0.47) | ALDH1A1MAPTDGKATSHRKDM4E | |
| SCHEMBL13868503 | 0.84 | DGKA (0.52) | ALDH1A1MAPTDGKALMNACYP3A4 | |
| SCHEMBL15113660 | 0.84 | MAPT (0.62) | ALDH1A1MAPTDGKALMNATSHR | |
| SCHEMBL15113661 | 0.84 | MAPT (0.62) | ALDH1A1MAPTDGKALMNATSHR | |
| SCHEMBL15113662 | 0.84 | MAPT (0.62) | ALDH1A1MAPTDGKALMNATSHR | |
| SCHEMBL15113664 | 0.84 | MAPT (0.62) | ALDH1A1MAPTDGKALMNATSHR | |
| SCHEMBL15113659 | 0.84 | MAPT (0.62) | ALDH1A1MAPTDGKALMNATSHR | |
| SCHEMBL15113667 | 0.84 | MAPT (0.62) | ALDH1A1MAPTDGKALMNATSHR | |
| SCHEMBL15113663 | 0.84 | MAPT (0.62) | ALDH1A1MAPTDGKALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962523-A | Methods of using butyric acid derivatives to protect against hair loss | DISCOVERY LABORATORIES, INC. (US) | 1999-10-05 | — | — | US | claimed |
| EP-0793488-A4 | — | — | 1997-09-10 | — | — | EP | claimed |
| EP-0793488-A1 | INCREASING FETAL HEMOGLOBIN LEVELS USING CARBOXYLIC ESTERS | Rephaeli, Ada (US) | 1997-09-10 | — | — | EP | claimed |
| US-5569675-A | ADMINISTERING TO TREAT BLOOD DISORDERS | BAR ILAN UNIVERSITY (IL) | 1996-10-29 | — | — | US | claimed |
| WO-1995024189-A1 | INCREASING FETAL HEMOGLOBIN LEVELS USING CARBOXYLIC ESTERS | REPHAELI ADA (US) | 1995-09-14 | — | — | WO | claimed |
| US-5962523-A | Methods of using butyric acid derivatives to protect against hair loss | DISCOVERY LABORATORIES, INC. (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0793488-A4 | — | — | 1997-09-10 | — | — | EP | disclosed |
| EP-0793488-A1 | INCREASING FETAL HEMOGLOBIN LEVELS USING CARBOXYLIC ESTERS | Rephaeli, Ada (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5569675-A | ADMINISTERING TO TREAT BLOOD DISORDERS | BAR ILAN UNIVERSITY (IL) | 1996-10-29 | — | — | US | disclosed |
| WO-1995024189-A1 | INCREASING FETAL HEMOGLOBIN LEVELS USING CARBOXYLIC ESTERS | REPHAELI ADA (US) | 1995-09-14 | — | — | WO | disclosed |