Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156827 | 0.86 | ALDH1A1 (0.56) | ALDH1A1LMNAMAOBRAB9AKMT2A | |
| SCHEMBL27687599 | 0.82 | TNKS (0.52) | ALDH1A1MAOBRAB9AKMT2AMEN1 | |
| SCHEMBL9754513 | 0.80 | ALDH1A1 (0.67) | ALDH1A1LMNAMAOBRAB9AKMT2A | |
| SCHEMBL6896489 | 0.79 | ALDH1A1 (0.48) | ALDH1A1LMNAMAOBRAB9AKMT2A | |
| SCHEMBL28506238 | 0.78 | ALDH1A1 (0.52) | ALDH1A1LMNAMAOBRAB9AKMT2A | |
| SCHEMBL5941127 | 0.76 | HPGD (0.56) | ALDH1A1LMNAMAOBRAB9AKMT2A | |
| SCHEMBL30422441 | 0.76 | HPGD (0.56) | ALDH1A1LMNAMAOBRAB9AKMT2A | |
| SCHEMBL9238022 | 0.76 | RAB9A (0.49) | ALDH1A1LMNAMAOBRAB9AKMT2A | |
| SCHEMBL8868150 | 0.75 | KMT2A (0.48) | ALDH1A1LMNAMAOBRAB9AKMT2A | |
| SCHEMBL8583022 | 0.75 | RAB9A (0.48) | ALDH1A1LMNAMAOBRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934270-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997045412-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1997-12-04 | — | — | WO | disclosed |