SCHEMBL8458

SCHEMBL8458

OCCCN1CCOCC1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
KDM4E B2RXH2 2/20 0.67
KEAP1 Q14145 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
HPGD P15428 1/20 0.53
DUSP3 P51452 1/20 0.53
GLA P06280 1/20 0.48
GAA P10253 1/20 0.47
SIGMAR1 Q99720 2/20 0.47
POLB P06746 1/20 0.47
LMNA P02545 3/20 0.46
USP2 O75604 2/20 0.44
MAPK1 P28482 3/20 0.43
PAOX Q6QHF9 1/20 0.43
HIF1A Q16665 1/20 0.43
CYP1A2 P05177 1/20 0.43
CHRM2 P08172 1/20 0.43
CHRM1 P11229 1/20 0.43
HTR2A P28223 1/20 0.43
SCN1A P35498 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL516842 0.98 ALDH1A1 (0.64) ALDH1A1KDM4EKEAP1SMN1; SMN2HPGD
SCHEMBL5661986 0.98 ALDH1A1 (0.71) ALDH1A1KDM4EKEAP1SMN1; SMN2HPGD
SCHEMBL22609104 0.95 ALDH1A1 (0.75) ALDH1A1KDM4EKEAP1SMN1; SMN2HPGD
SCHEMBL11087 0.93 KDM4E (0.64) ALDH1A1KDM4EKEAP1SMN1; SMN2HPGD
SCHEMBL19617043 0.91 ALDH1A1 (0.57) ALDH1A1KDM4EKEAP1SMN1; SMN2HPGD
SCHEMBL12014339 0.91 KDM4E (0.61) ALDH1A1KDM4EKEAP1SMN1; SMN2HPGD
SCHEMBL1403807 0.91 KDM4E (0.61) ALDH1A1KDM4EKEAP1SMN1; SMN2HPGD
SCHEMBL1403881 0.91 KDM4E (0.61) ALDH1A1KDM4EKEAP1SMN1; SMN2HPGD
SCHEMBL12014344 0.91 KDM4E (0.61) ALDH1A1KDM4EKEAP1SMN1; SMN2HPGD
SCHEMBL12014335 0.91 KDM4E (0.61) ALDH1A1KDM4EKEAP1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3677 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4667511-A2 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY Tiba Biotech LLC (US) 2025-12-24 EP claimed
CN-119493348-A Photoresist stripping liquid and preparation method and application thereof 福建泓光半导体材料有限公司 2025-02-21 CN claimed
CN-118852129-A Preparation method and application of triazole feed additive with anti-inflammatory activity designed based on deep learning technology 河南湾流生物科技有限公司 2024-10-29 CN claimed
CN-111936487-B Compounds for the treatment of kinase dependent disorders 埃克塞里艾克西斯公司 2024-07-09 CN claimed
US-20240207187-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY TIBA BIOTECH LLC (US) 2024-06-27 US claimed
CN-118085973-A Post-chemical mechanical polishing formulations and methods of use thereof 恩特格里斯公司 2024-05-28 CN claimed
CN-118047735-A Preparation method of pramoxine 中国人民解放军空军军医大学 2024-05-17 CN claimed
US-20240158370-A1 CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. 2024-05-16 US claimed
US-20240150371-A1 Compounds for the Treatment of Kinase-Dependent Disorders EXELIXIS, INC. 2024-05-09 US claimed
CN-117794923-A Benzodioxane compound, and preparation method and application thereof 南京红云生物科技有限公司 2024-03-29 CN claimed
EP-0790986-A1 ANILINE DERIVATIVES ZENECA LIMITED (GB) 1997-08-27 EP claimed
WO-1996033980-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1996-10-31 WO claimed
WO-1996033977-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1996-10-31 WO claimed
WO-1996028448-A1 6-ARYL PYRAZOLO[3,4-d]PYRIMIDIN-4-ONES AND COMPOSITIONS AND METHODS OF USE THEREOF SANOFI WINTHROP, INC. (US) 1996-09-19 WO claimed
EP-0716077-A1 Aromatically substituted omega amino alcanoic acid amides and alcanoic diamides and their use as renine inhibitors CIBA-GEIGY AG (CH) 1996-06-12 EP claimed
WO-1996015118-A1 ANILINE DERIVATIVES ZENECA LIMITED (GB) 1996-05-23 WO claimed
US-5516915-A Bis-(1H-indol-3-yl)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them GOEDECKE AKTIENGESELLSCHAFT (DE) 1996-05-14 US claimed
EP-0370236-B1 INDOLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS GÖDECKE AKTIENGESELLSCHAFT (DE) 1991-12-27 EP claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
US-4026935-A FROM N-(HYDROXYALKYL)-MORPHOLINE COMPOUND, SILICA-ALUMINA CATALYST TEXACO DEVELOPMENT CORPORATION (US) 1977-05-31 US claimed