Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460695 | 1.00 | REN (0.50) | RENCTSDCTSE | |
| SCHEMBL8459146 | 0.86 | REN (0.40) | RENCTSD | |
| SCHEMBL8852989 | 0.86 | REN (0.40) | RENCTSD | |
| SCHEMBL7631860 | 0.83 | KLK5 (0.52) | REN | |
| SCHEMBL7631855 | 0.83 | KLK5 (0.52) | REN | |
| SCHEMBL8458792 | 0.82 | REN (0.57) | REN | |
| SCHEMBL8462589 | 0.82 | REN (0.57) | REN | |
| SCHEMBL7431245 | 0.80 | REN (0.57) | REN | |
| SCHEMBL7431241 | 0.80 | REN (0.57) | REN | |
| SCHEMBL8894934 | 0.80 | REN (0.54) | RENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935976-A | Antiviral ethers of aspartate protease substrate isosteres | NOVARTIS CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |
| US-5807891-A | RETROVIRUSES | NOVARTIS AG (CH) | 1998-09-15 | — | — | US | disclosed |
| US-5663200-A | CARBAMOYL PEPTIDE DERIVATIVES AS VIRICIDES | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0708085-A2 | Antiviral ethers of aspartate protease substrate isosteres | CIBA-GEIGY AG (CH) | 1996-04-24 | — | — | EP | disclosed |