SCHEMBL8458208

SCHEMBL8458208

N#CC(C#N)=Cc1ccccc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.62
APP P05067 3/20 0.49
KMT2A Q03164 6/20 0.48
MAPT P10636 6/20 0.48
MEN1 O00255 5/20 0.48
ALDH1A1 P00352 5/20 0.48
KDM4E B2RXH2 4/20 0.48
LMNA P02545 4/20 0.48
NPSR1 Q6W5P4 2/20 0.48
POLB P06746 1/20 0.48
SENP1 Q9P0U3 1/20 0.47
EGFR P00533 4/20 0.47
CYP2C9 P11712 3/20 0.47
TP53 P04637 2/20 0.47
CYP3A4 P08684 2/20 0.47
HPGD P15428 2/20 0.47
ALOX15 P16050 2/20 0.47
TSHR P16473 2/20 0.47
ALOX12 P18054 2/20 0.47
NFKB1 P19838 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10517794 0.83 TRPA1 (0.53) TRPA1APPKMT2AMAPTMEN1
SCHEMBL3369090 0.77 TRPA1 (0.60) TRPA1APPKMT2AMAPTMEN1
SCHEMBL29740451 0.77 TRPA1 (0.60) TRPA1APPKMT2AMAPTMEN1
SCHEMBL29404696 0.77 TRPA1 (1.00) TRPA1APPKMT2AMAPTMEN1
SCHEMBL17466935 0.77 TRPA1 (0.60) TRPA1APPKMT2AMAPTMEN1
SCHEMBL3369333 0.77 MAPT (0.63) TRPA1APPKMT2AMAPTMEN1
SCHEMBL436060 0.77 TRPA1 (1.00) TRPA1APPKMT2AMAPTMEN1
SCHEMBL3368866 0.77 TRPA1 (0.60) TRPA1APPKMT2AMAPTMEN1
SCHEMBL21457540 0.76 CA12 (0.52) TRPA1APPKMT2AMAPTMEN1
SCHEMBL29492373 0.75 EGFR (0.54) TRPA1KMT2AMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11334206-A None JP disclosed
CN-115232089-B Vinyl phenol thiazine fluorescent probe and preparation method and application thereof 洛阳师范学院 2024-11-15 CN disclosed
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed
JP-H11334206-A OPTICAL RECORDING MEDIUM MITSUBISHI CHEMICAL CORP 1999-12-07 JP disclosed