SCHEMBL29404696

SCHEMBL29404696

N#CC(C#N)=Cc1ccccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 1.00
APP P05067 3/20 0.47
ALDH1A1 P00352 4/20 0.46
MAPT P10636 4/20 0.46
KDM4E B2RXH2 3/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
ATM Q13315 1/20 0.46
TP53 P04637 2/20 0.43
THRB P10828 1/20 0.43
SNCA P37840 1/20 0.43
GAA P10253 1/20 0.43
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL436060 1.00 TRPA1 (1.00) TRPA1APPALDH1A1MAPTKDM4E
SCHEMBL2726862 0.84 TRPA1 (0.72) TRPA1APPALDH1A1MAPTKDM4E
SCHEMBL11436243 0.80 TRPA1 (0.67) TRPA1ALDH1A1MAPTKDM4EKMT2A
SCHEMBL13485328 0.79 TRPA1 (0.65) TRPA1APPALDH1A1MAPTKMT2A
SCHEMBL6839476 0.77 TRPA1 (0.62) TRPA1APPALDH1A1MAPTKDM4E
SCHEMBL8458208 0.77 TRPA1 (0.62) TRPA1APPALDH1A1MAPTKDM4E
SCHEMBL271573 0.76 TRPA1 (0.61) TRPA1ALDH1A1MAPTKDM4EKMT2A
SCHEMBL272063 0.76 GABRA1 (0.69) TRPA1ALDH1A1MAPTKDM4EKMT2A
SCHEMBL10733520 0.76 TRPA1 (0.61) TRPA1ALDH1A1MAPTKDM4EKMT2A
SCHEMBL10733517 0.76 TRPA1 (0.61) TRPA1ALDH1A1MAPTKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119925624-A Liver targeting compound and conjugate, preparation method and application thereof 上海数因信科智能科技有限公司 2025-05-06 CN claimed
CN-119925624-A Liver targeting compound and conjugate, preparation method and application thereof 上海数因信科智能科技有限公司 2025-05-06 CN disclosed
CN-119331036-A Tri-cluster galactose compound, conjugate, preparation method and application thereof 广州市锐博生物科技有限公司 2025-01-21 CN disclosed
CN-119113136-A Application of RNAi agent in treating periodontitis and related diseases 北京瑞博开拓医药科技有限公司 2024-12-13 CN disclosed
US-12151573-B2 Vehicle charging using a multi-drive system GM Global Technology Operations LLC (US) 2024-11-26 US disclosed
US-20240247693-A1 CLUTCH SYSTEM FOR SELECTIVE ENGAGEMENT OF A VEHICLE DRIVE SYSTEM GM Global Technology Operations LLC 2024-07-25 US disclosed
CN-118372645-A Clutch system for selectively engaging a vehicle drive system 通用汽车环球科技运作有限责任公司 2024-07-23 CN disclosed
WO-2024073678-A2 PHOSPHOLIPIDS CONTAINING A HETEROCYCLE RING HAVING A TERTIARY AMINE OR AMIDE OMEGA THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed
US-20240092203-A1 VEHICLE CHARGING USING A MULTI-DRIVE SYSTEM GM Global Technology Operations LLC 2024-03-21 US disclosed
US-11929475-B2 Battery heating during vehicle operation and/or during vehicle charging GM Global Technology Operations LLC (US) 2024-03-12 US disclosed
CN-117325718-A Battery heating during vehicle operation and/or during vehicle charging 通用汽车环球科技运作有限责任公司 2024-01-02 CN disclosed
US-20230420763-A1 BATTERY HEATING DURING VEHICLE OPERATION AND/OR DURING VEHICLE CHARGING GM Global Technology Operations LLC 2023-12-28 US disclosed
CN-117087457-A Charging and/or from a vehicle using an expandable buck-boost system 通用汽车环球科技运作有限责任公司 2023-11-21 CN disclosed
US-20230365012-A1 CHARGING TO AND/OR FROM A VEHICLE USING A SCALABLE BUCK-BOOST SYSTEM GM Global Technology Operations LLC 2023-11-16 US disclosed
CN-116980891-A Method and device for generating underwater sound physical layer key based on MIMO 中国人民解放军战略支援部队信息工程大学 2023-10-31 CN disclosed
US-11444474-B1 Apparatus for mobile power source GM Global Technology Operations LLC (US) 2022-09-13 US disclosed
CN-115051421-A Device for mobile power supply 通用汽车环球科技运作有限责任公司 2022-09-13 CN disclosed
US-20220285959-A1 APPARATUS FOR MOBILE POWER SOURCE GM Global Technology Operations LLC 2022-09-08 US disclosed
CN-114630838-A Novel anti-CD 25 antibodies 法国国家健康和医学研究院 2022-06-14 CN disclosed
EP-3966793-A1 NON-LETHAL DISTRACTION AND GLASS, METHOD OF ENTRY DEVICES Rogers, Stephen (GB) 2022-03-16 EP disclosed