Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.32 |
| ▸ | RARG | P13631 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | GOT1 | P17174 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459321 | 0.77 | RARB (0.39) | RARBRARGKMT2AMEN1RARA | |
| SCHEMBL8458440 | 0.75 | RARB (0.40) | RARBRARGKMT2AMEN1RARA | |
| SCHEMBL8459326 | 0.73 | KMT2A (0.40) | RARBRARGKMT2AMEN1RARA | |
| SCHEMBL7920732 | 0.73 | RARB (0.43) | RARBRARGKMT2AMEN1RARA | |
| SCHEMBL8457116 | 0.72 | RARB (0.48) | RARBRARGKMT2AMEN1RARA | |
| SCHEMBL8457476 | 0.72 | RARB (0.44) | RARBRARGKMT2AMEN1RARA | |
| SCHEMBL8455780 | 0.71 | RARB (0.38) | RARBRARGKMT2AMEN1RARA | |
| SCHEMBL7926560 | 0.70 | RARB (0.45) | RARBRARGKMT2AMEN1RARA | |
| SCHEMBL8459014 | 0.70 | CNR2 (0.31) | HIF1A | |
| SCHEMBL8458022 | 0.69 | PTPN11 (0.44) | RARBRARGKMT2AMEN1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952382-A | INHIBITING THE BIOLOGICAL EFFECTS OF AN OVERREGULATION OF RETINOID ACID RECEPTORS AND/OR OF A HYPERVITAMINOSIS A; TREATING SKIN DISORDER, EYE VISION DEFECTS, SKIN AGING | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-09-14 | — | — | US | disclosed |