SCHEMBL8461591

SCHEMBL8461591

C=CC(=O)OCC[Si](OCCC)(OCCC)OCCC

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.56
HPGD P15428 1/20 0.56
ALDH1A1 P00352 4/20 0.47
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
CYP3A4 P08684 2/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 4/20 0.44
HCAR2 Q8TDS4 4/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ATM Q13315 1/20 0.37
APP P05067 1/20 0.33
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28013523 0.95 TSHR (0.51) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL949700 0.90 TSHR (0.62) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8458247 0.90 TSHR (0.68) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL270021 0.87 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL949699 0.87 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL4249650 0.85 TSHR (0.57) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28329096 0.85 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1064310 0.84 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL237274 0.84 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1068273 0.83 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110320746-B Radiation-sensitive composition, cured film, method for producing same, display element, and display device JSR株式会社 2024-09-06 CN disclosed
CN-117148676-A Negative photoresist composition for organic insulating film of liquid crystal display element 烟台希尔德材料科技有限公司 2023-12-01 CN disclosed
CN-113444373-B Composition for modifying asphalt, modified asphalt, method for producing same, and asphalt mixture 李威风 2023-01-24 CN disclosed
WO-2022042662-A1 BIONIC AND DUAL-PHOBIC HIGH-PERFORMANCE WATER-BASED DRILLING FLUID 中国石油大学(北京) 2022-03-03 WO disclosed
CN-108300385-B Adhesive sheet, display, and method for producing same 琳得科株式会社 2022-02-15 CN disclosed
CN-113444373-A Composition for modifying asphalt, modified asphalt, method for producing same, and asphalt mixture 李威风 2021-09-28 CN disclosed
US-20160299376-A1 LIQUID CRYSTAL DISPLAY DEVICE, RADIATION-SENSITIVE RESIN COMPOSITION, INTERLAYER INSULATING FILM, METHOD FOR PRODUCING INTERLAYER INSULATING FILM, AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE JSR CORPORATION (JP) 2016-10-13 US disclosed
CN-102955188-B The manufacture method of colored filter, liquid crystal display cells and colored filter JSR CO., LTD. (JP) 2015-12-09 CN disclosed
CN-104820340-A Manufacturing method for hardened film of display element, photoreceptive and radioactive resin composition, applications and heating device JSR KK 2015-08-05 CN disclosed
CN-102566278-B Siloxane polymer composition, cured film and method for forming the cured film JSR CORP 2015-01-21 CN disclosed
US-20140014928-A1 ORGANIC EL ELEMENT, RADIATION-SENSITIVE RESIN COMPOSITION, AND CURED FILM JSR CORPORATION (JP) 2014-01-16 US disclosed
CN-102419515-B Polysiloxane compound, preparation method of polysiloxane compound, solidified film of display element and formation method of solidified film JSR KK 2013-06-12 CN disclosed
CN-102955188-A Color filter, liquid crystal display element, and method for producing the color filter JSR CORP 2013-03-06 CN disclosed
CN-101515113-B Radioactive ray sensibility resin composition, interlayer insulating film, microlens and method of forming the same JSR CORP 2012-07-18 CN disclosed
CN-102566278-A Siloxane polymer composition, cured film and method for forming the cured film JSR CORP 2012-07-11 CN disclosed
CN-102419515-A Silicone composition, method for producing silicone composition, cured film of display element, and method for forming cured film of display element JSP KK 2012-04-18 CN disclosed
EP-0604677-B1 Method of making coated shaped articles MITSUBISHI RAYON CO (JP) 1999-08-11 EP disclosed
US-5470616-A Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1995-11-28 US disclosed
EP-0604677-A1 Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1994-07-06 EP disclosed
US-4026826-A ALKOXYSILANES JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1977-05-31 US disclosed