Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461462 | 0.83 | ATM (0.44) | MAPTSMN1; SMN2TDP1LMNAMEN1 | |
| SCHEMBL8461460 | 0.78 | CYP2C9 (0.55) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8458233 | 0.75 | MAPT (0.46) | ELANEMAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL8458276 | 0.74 | HDAC3 (0.53) | MAPTSMN1; SMN2LMNAGAAMEN1 | |
| SCHEMBL28167770 | 0.72 | MAPT (0.69) | ELANEMAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL232724 | 0.72 | RAB9A (0.74) | MAPTSMN1; SMN2TDP1LMNAMEN1 | |
| SCHEMBL10938383 | 0.72 | HDAC10 (0.50) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL27707538 | 0.72 | ELANE (0.89) | ELANEMAPTTDP1LMNAGAA | |
| SCHEMBL134239 | 0.70 | MAPT (0.65) | MAPTSMN1; SMN2TDP1LMNAMEN1 | |
| SCHEMBL13534566 | 0.70 | RAB9A (0.78) | MAPTSMN1; SMN2TDP1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859042-A | ALOPECIA, ACNE, DISEASES OF THE PROSTATE GLANDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | claimed |