Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21359198 | 0.83 | CXCL8 (0.54) | SMN1; SMN2ELANESCN1ASCN2ASCN3A | |
| SCHEMBL8729574 | 0.83 | HDAC10 (0.41) | MAPTSMN1; SMN2SCN1ASCN2ASCN3A | |
| SCHEMBL27370571 | 0.82 | CXCL8 (0.52) | SMN1; SMN2ELANESCN1ASCN2ASCN3A | |
| SCHEMBL8461622 | 0.82 | CES2 (0.42) | MAPTSMN1; SMN2ELANELMNAMEN1 | |
| SCHEMBL8729572 | 0.80 | CDC25B (0.51) | MAPTSMN1; SMN2CDC25BATMLMNA | |
| SCHEMBL8459798 | 0.78 | TTR (0.46) | MAPTSMN1; SMN2HSD17B10ATMLMNA | |
| SCHEMBL10939182 | 0.78 | EGFR (0.48) | MAPTSMN1; SMN2HSD17B10SCN1ASCN2A | |
| SCHEMBL8458277 | 0.75 | ELANE (0.47) | MAPTSMN1; SMN2ELANEHSD17B10TDP1 | |
| SCHEMBL8458232 | 0.73 | PTGS1 (0.74) | MAPTSMN1; SMN2CDC25BATMLMNA | |
| SCHEMBL8729395 | 0.71 | CXCL8 (0.55) | SMN1; SMN2HSD17B10LMNAGAACXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859042-A | ALOPECIA, ACNE, DISEASES OF THE PROSTATE GLANDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |