Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pimelic Acid SCHEMBL10652387 | 0.98 | WDR5 (0.53) | WDR5LDHACYP1A2CYP2C19CYP2D6 | |
| Glutarate SCHEMBL8897138 | 0.97 | WDR5 (0.54) | WDR5LDHACYP1A2CYP2C19CYP2D6 | |
| Succinic Acid SCHEMBL8896782 | 0.93 | WDR5 (0.58) | WDR5LDHACYP1A2CYP2C19CYP2D6 | |
| Succinic Acid SCHEMBL28562591 | 0.89 | WDR5 (0.53) | WDR5LDHACYP1A2CYP2C19CYP2D6 | |
| Benzene SCHEMBL27549874 | 0.88 | WDR5 (0.68) | WDR5LDHACYP1A2CYP2C19KDM4E | |
| SCHEMBL27804512 | 0.88 | WDR5 (0.68) | WDR5LDHACYP1A2CYP2C19KDM4E | |
| SCHEMBL29376013 | 0.88 | WDR5 (0.68) | WDR5LDHACYP1A2CYP2C19KDM4E | |
| SCHEMBL33850 | 0.88 | WDR5 (0.68) | WDR5LDHACYP1A2CYP2C19KDM4E | |
| Naphthalene SCHEMBL1831655 | 0.86 | WDR5 (0.66) | WDR5LDHACYP1A2CYP2C19KDM4E | |
| Ammonia Solution, Strong SCHEMBL8803959 | 0.86 | WDR5 (0.66) | WDR5LDHACYP1A2CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559785-B1 | Blends of aliphatic-aromatic copolyesters with cellulose ester polymers | EASTMAN CHEM CO (US) | 1997-03-12 | — | — | EP | claimed |
| EP-0934201-A1 | TRANSPARENT OXYGEN-SCAVENGING ARTICLE INCLUDING BIAXIALLY-ORIENTED POLYESTER | CONTINENTAL PET TECHNOLOGIES, INC. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998013266-A9 | TRANSPARENT OXYGEN-SCAVENGING ARTICLE INCLUDING BIAXIALLY-ORIENTED POLYESTER | — | 1998-05-22 | — | — | WO | disclosed |
| WO-1998013266-A1 | TRANSPARENT OXYGEN-SCAVENGING ARTICLE INCLUDING BIAXIALLY-ORIENTED POLYESTER | CONTINENTAL PET TECHNOLOGIES, INC. (US) | 1998-04-02 | — | — | WO | disclosed |