Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28562591 | 0.95 | WDR5 (0.53) | WDR5LDHAALDH1A1HPGDCYP1A2 | |
| Glutarate SCHEMBL8897138 | 0.93 | WDR5 (0.54) | WDR5LDHAALDH1A1HPGDCYP1A2 | |
| Adipic Acid SCHEMBL8458281 | 0.93 | WDR5 (0.54) | WDR5LDHAALDH1A1HPGDCYP1A2 | |
| Pimelic Acid SCHEMBL10652387 | 0.92 | WDR5 (0.53) | WDR5LDHAALDH1A1HPGDCYP1A2 | |
| SCHEMBL27804512 | 0.91 | WDR5 (0.68) | WDR5LDHAALDH1A1HPGDCYP1A2 | |
| Benzene SCHEMBL27549874 | 0.91 | WDR5 (0.68) | WDR5LDHAALDH1A1HPGDCYP1A2 | |
| SCHEMBL29376013 | 0.91 | WDR5 (0.68) | WDR5LDHAALDH1A1HPGDCYP1A2 | |
| SCHEMBL33850 | 0.91 | WDR5 (0.68) | WDR5LDHAALDH1A1HPGDCYP1A2 | |
| Potassium SCHEMBL9788816 | 0.89 | WDR5 (0.66) | WDR5LDHAALDH1A1HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL608188 | 0.89 | LDHA (0.69) | WDR5LDHAALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559785-B1 | Blends of aliphatic-aromatic copolyesters with cellulose ester polymers | EASTMAN CHEM CO (US) | 1997-03-12 | — | — | EP | claimed |
| CN-112934150-B | Biodegradable copolyester production system, preparation method and copolyester | 中国纺织科学研究院有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-112794996-B | Preparation system and preparation method of biodegradable copolyester and copolyester thereof | 中国纺织科学研究院有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-112934150-A | Biodegradable copolyester production system, preparation method and copolyester | 中国纺织科学研究院有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-112794996-A | Preparation system and preparation method of biodegradable copolyester and copolyester thereof | 中国纺织科学研究院有限公司 | 2021-05-14 | — | — | CN | disclosed |