Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2485452 | 1.00 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL4740630 | 1.00 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL129577 | 1.00 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL7839213 | 1.00 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL7839840 | 1.00 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL8453125 | 1.00 | DGKA (0.68) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL129849 | 0.98 | DGKA (0.64) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL7838000 | 0.94 | DGKA (0.71) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL1888899 | 0.94 | DGKA (0.71) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL7839300 | 0.94 | DGKA (0.71) | DGKAPRSS1PRSS2PRSS3DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691327-B1 | AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME | KAO CORP (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5723497-A | AMINE ALCOHOL DERIVATIVES FOR WRINKLE RESISTNCE | KAO CORPORATION (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0691327-A1 | AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME | Kao Corporation (JP) | 1996-01-10 | — | — | EP | disclosed |