Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.67 |
| ▸ | RXRB | P28702 | 12/20 | 0.67 |
| ▸ | RXRG | P48443 | 9/20 | 0.67 |
| ▸ | RARB | P10826 | 7/20 | 0.58 |
| ▸ | RARG | P13631 | 7/20 | 0.58 |
| ▸ | RARA | P10276 | 5/20 | 0.58 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.57 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674739 | 0.92 | RXRA (0.65) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8461369 | 0.85 | RXRA (0.64) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8839229 | 0.82 | RXRA (0.64) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8108593 | 0.81 | RXRA (0.66) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8100970 | 0.81 | RXRA (0.66) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9208986 | 0.81 | RXRA (0.78) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8675649 | 0.80 | RXRA (0.62) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8839098 | 0.80 | RXRA (0.64) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8459952 | 0.77 | RXRA (0.66) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL5084734 | 0.77 | CYP26B1 (0.75) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048529-A1 | RETINOID-GLITAZONE COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-09-30 | — | — | WO | disclosed |
| EP-0808159-A1 | USE OR RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024344-A1 | USE OF RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1996-08-15 | — | — | WO | disclosed |
| US-5489611-A | ADMINISTERING A RETINOID COMPOUND | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |