Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.53 |
| ▸ | RARB | P10826 | 3/20 | 0.53 |
| ▸ | RARG | P13631 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | GOT1 | P17174 | 1/20 | 0.53 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459618 | 0.88 | RARA (0.53) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8460300 | 0.86 | RARA (0.52) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8457611 | 0.86 | RARA (0.52) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL565789 | 0.79 | RARA (0.77) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL1082340 | 0.79 | RARA (0.77) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8459230 | 0.79 | RARA (0.54) | RARARARBRARGMEN1KMT2A | |
| Benzoic Acid SCHEMBL9268624 | 0.78 | RARA (0.64) | RARARARBRARGMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9124255 | 0.78 | RARA (0.76) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL9078617 | 0.76 | RARA (0.64) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8839053 | 0.76 | RARA (0.55) | RARARARBRARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869067-A | TREATING DERMATOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1999-02-09 | — | — | US | claimed |
| US-5869067-A | TREATING DERMATOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1999-02-09 | — | — | US | disclosed |
| US-5753239-A | Bi-aromatic compounds and pharmaceutical and cosmetic compositions | CENTRE INTERNATIONAL DE RECHERCHES DEMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1998-05-19 | — | — | US | disclosed |