Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089496 | 0.83 | RECQL (0.40) | ALDH1A1HIF1ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL28014000 | 0.81 | CYP2C19 (0.46) | ALDH1A1HIF1ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL27822150 | 0.80 | CYP2C19 (0.43) | ALDH1A1HIF1ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL9189250 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HIF1ASMN1; SMN2CYP1A2CYP2C19 | |
| Phosphine SCHEMBL6248436 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HIF1ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8462886 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HIF1ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL30229451 | 0.76 | CYP1A2 (0.41) | ALDH1A1HIF1ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL9246907 | 0.76 | TSHR (0.41) | HIF1ASMN1; SMN2CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11605570 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HIF1ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL2878828 | 0.76 | PPARG (0.56) | ALDH1A1HIF1ASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5989527-A | Compositions and methods for improving the performance of chemical exfoliating agents, sunless tanning agents, skin lightening agents and insect repellents | INOLEX INVESTMENT CORPORATION (US) | 1999-11-23 | — | — | US | disclosed |