SCHEMBL30229451

SCHEMBL30229451

CC(=O)OC(C)(C)c1ccccc1.CC(C)(Cc1ccccc1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.41
CYP3A4 P08684 2/20 0.41
RECQL P46063 2/20 0.41
ALDH1A1 P00352 4/20 0.41
CYP2C19 P33261 4/20 0.41
HIF1A Q16665 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 2/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
CYP2C9 P11712 2/20 0.40
KCNH2 Q12809 2/20 0.38
OPRM1 P35372 2/20 0.38
OPRD1 P41143 2/20 0.38
MRGPRX2 Q96LB1 1/20 0.38
CHRM3 P20309 1/20 0.38
HRH2 P25021 1/20 0.38
HTR2A P28223 1/20 0.38
ADRA1A P35348 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL42458 0.83 ALDH1A1 (0.56) CYP1A2CYP3A4ALDH1A1CYP2C19HIF1A
SCHEMBL517462 0.82 SMN1; SMN2 (0.57) CYP1A2CYP3A4RECQLALDH1A1CYP2C19
SCHEMBL28246706 0.80 HIF1A (0.55) CYP1A2CYP3A4RECQLALDH1A1CYP2C19
SCHEMBL28727407 0.80 SMN1; SMN2 (0.55) CYP1A2CYP3A4RECQLALDH1A1CYP2C19
SCHEMBL8459554 0.76 ALDH1A1 (0.44) CYP1A2CYP3A4RECQLALDH1A1CYP2C19
SCHEMBL9189250 0.76 ALDH1A1 (0.47) CYP1A2CYP3A4RECQLALDH1A1CYP2C19
SCHEMBL2878828 0.76 PPARG (0.56) CYP1A2CYP3A4RECQLALDH1A1CYP2C19
SCHEMBL111212 0.75 ALDH1A1 (0.50) CYP1A2CYP3A4RECQLALDH1A1CYP2C19
Phosphine SCHEMBL6248436 0.74 ALDH1A1 (0.46) CYP1A2CYP3A4RECQLALDH1A1CYP2C19
SCHEMBL305335 0.74 ALDH1A1 (0.39) CYP1A2CYP3A4ALDH1A1CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115701977-A Composition for treating hair or fiber comprising alkylketene compound 株式会社LG生活健康 2023-02-14 CN disclosed