Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227267 | 0.93 | HPGD (0.48) | PTK2BKMT2AMEN1NPSR1HPGD | |
| SCHEMBL11229789 | 0.86 | NPC1 (0.47) | KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8459689 | 0.81 | MAPT (0.51) | KMT2AMEN1HPGDMAPTALDH1A1 | |
| SCHEMBL11223906 | 0.80 | RXRA (0.46) | KMT2ARXRARXRBMAPTALDH1A1 | |
| SCHEMBL11229792 | 0.80 | MRGPRX4 (0.48) | KMT2ANPSR1HPGDMAPTALDH1A1 | |
| SCHEMBL3149726 | 0.77 | PTK2B (0.51) | PTK2BKMT2AMEN1NPSR1HPGD | |
| SCHEMBL7051957 | 0.77 | PTK2B (0.51) | PTK2BKMT2AMEN1NPSR1HPGD | |
| SCHEMBL5706002 | 0.77 | KMT2A (0.63) | PTK2BKMT2AMEN1NPSR1HPGD | |
| SCHEMBL17671405 | 0.76 | PTGS2 (0.47) | KMT2ANPSR1RXRARXRBMAPT | |
| Phosphoric Acid SCHEMBL8462680 | 0.76 | MAPT (0.47) | KMT2AMEN1HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329443-A | Process for polyester-carbonate transesterifications | GENERAL ELECTRIC COMPANY (US) | 1982-05-11 | — | — | US | disclosed |