SCHEMBL8460362

SCHEMBL8460362

C#CCc1cccc(S(=O)(=O)O)c1I=O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.34
PTGS2 P35354 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3891395 0.79 MYC (0.42) TTRPTGS2CYP1A2
SCHEMBL31619517 0.79 MYC (0.42) TTRPTGS2CYP1A2
SCHEMBL8463936 0.74 HMGB1 (0.38)
SCHEMBL8523178 0.74 AKR1B1 (0.42) TTRPTGS2CYP1A2
SCHEMBL8464218 0.74 TTR (0.34) TTRPTGS2CYP1A2
Phosphoric Acid SCHEMBL8462758 0.73 PTGS2 (0.39) PTGS2
SCHEMBL27363494 0.73 TTR (0.33) TTRPTGS2
SCHEMBL8463668 0.70 TTR (0.39) TTRCYP1A2
SCHEMBL8462755 0.70 INPPL1 (0.47)
SCHEMBL2702841 0.68 MITF (0.41) TTRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0745326-B1 Stabilization of aqueous 3-isothiazolone solutions ROHM & HAAS (US) 1999-09-22 EP disclosed
US-5594017-A WITH AN IODOSYL OR IODYL COMPOUND ROHM AND HAAS COMPANY (US) 1997-01-14 US disclosed
EP-0745326-A1 Stabilization of aqueous 3-isothiazolone solutions ROHM AND HAAS COMPANY (US) 1996-12-04 EP disclosed