Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463210 | 0.86 | — | — | |
| SCHEMBL8458674 | 0.85 | CA2 (0.37) | MAPK1POLBCA2CA1FDPS | |
| SCHEMBL8463312 | 0.79 | — | — | |
| SCHEMBL14519713 | 0.79 | CHRM1 (0.39) | MAPK1L3MBTL1HSD17B10POLBCA2 | |
| SCHEMBL8459359 | 0.78 | CA2 (0.41) | MAPK1POLBCA2CA1FDPS | |
| SCHEMBL8462488 | 0.77 | HSD17B10 (0.35) | MAPK1L3MBTL1HSD17B10POLBCA2 | |
| SCHEMBL8459268 | 0.77 | CHRM1 (0.40) | MAPK1CA2CHRM1AKR1A1CHRM3 | |
| SCHEMBL8460018 | 0.76 | TSHR (0.35) | MAPK1CA2TSHRCA1 | |
| SCHEMBL343756 | 0.73 | TSHR (0.50) | MAPK1L3MBTL1HSD17B10POLBCHRM1 | |
| SCHEMBL8461355 | 0.73 | MMP1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646605-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-06-02 | — | — | EP | disclosed |
| US-5468704-A | Comprising titanium halide or halogen alcoholate supported on magnesium halide and a diketone electron donor; preparing polypropylene of high isotacticity | MONTELL NORTH AMERICA INC. (US) | 1995-11-21 | — | — | US | disclosed |
| EP-0646605-A1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1995-04-05 | — | — | EP | disclosed |