Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463798 | 0.85 | L3MBTL1 (0.33) | ALDH1A1L3MBTL1MAPTTSHRPOLB | |
| SCHEMBL8463794 | 0.85 | L3MBTL1 (0.33) | ALDH1A1L3MBTL1MAPTTSHRPOLB | |
| SCHEMBL8463043 | 0.76 | TSHR (0.44) | ALDH1A1L3MBTL1MAPTTSHRPOLB | |
| Water SCHEMBL27479342 | 0.75 | TSHR (0.42) | ALDH1A1L3MBTL1MAPTTSHRPOLB | |
| SCHEMBL8463490 | 0.74 | TSHR (0.41) | ALDH1A1L3MBTL1MAPTTSHRPOLB | |
| SCHEMBL8463392 | 0.72 | BRD4 (0.31) | — | |
| SCHEMBL9946148 | 0.67 | TSHR (0.57) | ALDH1A1MAPTTSHRHSD17B10MEN1 | |
| SCHEMBL23302265 | 0.66 | MEN1 (0.44) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL1190834 | 0.65 | TSHR (0.57) | ALDH1A1L3MBTL1MAPTTSHRPOLB | |
| SCHEMBL7027565 | 0.64 | TSHR (0.55) | ALDH1A1L3MBTL1MAPTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949243-A1 | OPTICALLY ACTIVE METHOXYIMINOACETAMIDE DERIVATIVES, PROCESS FOR THE PREPARATION OF THEM, INTERMEDIATES THEREFOR, AND PESTICIDES CONTAINING THEM AS THE ACTIVE INGREDIENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-10-13 | — | — | EP | disclosed |