SCHEMBL9946148

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21957883	0.77	TSHR (0.50)	TSHRHSD17B10ALDH1A1KDM4EMAPT
	SCHEMBL6984021	0.76	L3MBTL1 (0.50)	TSHRHSD17B10ALDH1A1KDM4ECYP1A2
	SCHEMBL16752384	0.75	TSHR (0.65)	TSHRHSD17B10ALDH1A1KDM4EMAPT
	SCHEMBL28627549	0.75	TSHR (0.48)	TSHRHSD17B10ALDH1A1KDM4EMAPT
	Diethyl Phthalate SCHEMBL5306972	0.75	TSHR (1.00)	TSHRHSD17B10ALDH1A1KDM4EMAPT
	Diethyl Phthalate SCHEMBL22296	0.75	TSHR (1.00)	TSHRHSD17B10ALDH1A1KDM4EMAPT
	Diethyl Phthalate SCHEMBL29404255	0.75	TSHR (1.00)	TSHRHSD17B10ALDH1A1KDM4EMAPT
	SCHEMBL5386421	0.74	TSHR (0.62)	TSHRHSD17B10ALDH1A1KDM4EMAPT
	Diethyl Phthalate SCHEMBL8577506	0.73	TSHR (0.95)	TSHRHSD17B10ALDH1A1KDM4EMAPT
	Diethyl Phthalate SCHEMBL28775845	0.73	TSHR (0.95)	TSHRHSD17B10ALDH1A1KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.