Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 20/20 | 0.46 |
| ▸ | HTR1B | P28222 | 13/20 | 0.45 |
| ▸ | HTR1D | P28221 | 13/20 | 0.45 |
| ▸ | HTR1A | P08908 | 12/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010356 | 0.86 | HTR1F (0.47) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7017196 | 0.76 | HTR1F (0.54) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7008470 | 0.76 | HTR1F (0.56) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL30908990 | 0.76 | HTR1F (0.56) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7011970 | 0.69 | HTR1F (0.82) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7009030 | 0.69 | HTR1F (0.79) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7013755 | 0.69 | HTR1F (0.67) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7011609 | 0.69 | HTR1F (0.53) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7011607 | 0.69 | HTR1F (0.53) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7008169 | 0.69 | HTR1F (0.74) | HTR1FHTR1BHTR1DHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
| US-5998622-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | ELI LILLY AND COMPANY (US) | 1999-12-07 | — | — | US | disclosed |